Carbon analysis started in the 1630s when scientist Jan Baptist van Helmont discovered Carbon Dioxide. In 1756, Joseph Black discovered a way to measure Carbon Dioxide, and the method became more refined in 1924. American Cyanamid developed the infrared gas analyzer in 1948, and in 1967, DOW chemical patented a carbon content measuring system that manually injected aqueous samples directly into a gas stream of oxygen. Since that time, manufacturers have made a number of technology advances to continue to meet customers changing needs.
Labs in the biotech and pharmaceutical industries use TOC in cleaning validation procedures, including Clean-in-Place. TOC concentration levels can also be used to track success of cleaning procedures to ensure there is no cross-contamination. Protecting drinking water is a major focus for local, state and national organizations and governments, and TOC analysis popularity has increased because of the need to test wastewater and municipal water for organic matter. The guide reads, “When high organic content water is subjected to the disinfection process during normal purification, it will create disinfection by-products, which are carcinogenic. It is important to make sure the TOC is low in water coming in and water leaving the water treatment facility to ensure public safety.”
The guide reviews three primary oxidation techniques used by TOC analyzers today:
The guide also reviews they types, strengths and weaknesses of NDIR detectors, including their inability to handle halogenated compounds and their challenges with moisture. Teledyne also highlights other detection methods, including:
For additional details about oxidation and detection techniques, and Teledyne’s recommended processes, download the guide from TeledyneTekmar.com.
edited on 2/26/2021 to update correct spelling of Jan Baptist van Helmont